Spravato® Treatment

Esketamine Nasal Spray for Treatment-Resistant Depression


At Foundations Psychiatry in St. George, Utah, we provide Spravato® (esketamine) treatment for adults struggling with treatment-resistant depression (TRD) and severe depressive symptoms that have not improved with traditional antidepressants.


Spravato is an FDA-approved nasal spray medication that is administered in a safe, supervised clinical setting. Our Spravato program serves patients throughout Southern Utah, including surrounding communities.


If you are searching for Spravato treatment in in St. George, Utah, or options for depression that has not responded to medication, our clinic can help.


What is Spravato (Esketamine)?


Spravato® (esketamine) is an FDA-approved nasal spray medication used in combination with an oral antidepressant for:


  • Treatment-resistant depression (TRD)
  • Major depressive disorder (MDD) with suicidal thoughts or symptoms


Unlike traditional antidepressants, Spravato works on the brain’s glutamate system (NMDA receptors), which plays a key role in mood regulation and neural connections.


Because of this unique mechanism, Spravato may provide relief when SSRIs and SNRIs have not been effective.


At Foundations Psychiatry, Spravato treatments are provided in-office under direct medical supervision in our St. George clinic.


Our clinic provides:


  • Spravato-certified treatment administration
  • Experienced psychiatric providers
  • Private, comfortable treatment environment
  • Close monitoring during every session
  • Integrated mental health treatment planning
  • Insurance coordination and support


We are committed to providing high-quality depression treatment options for patients across Southern Utah.

Frequently Asked Questions About Spravato:

  • Who is a Candidate for Spravato?

    You may be a candidate for Spravato treatment if you:


    • Have tried two or more antidepressants without sufficient improvement
    • Continue to experience moderate to severe depression symptoms
    • Have treatment-resistant depression (TRD)
    • Experience worsening depression or suicidal thoughts despite treatment

    A full psychiatric evaluation at Foundations Psychiatry is required to determine eligibility.

  • How long does Spravato take to work?

    Some patients notice improvement within the first few weeks, while others experience gradual improvement over the course of treatment.

  • Do I need a referral for Spravato in Utah?

    A psychiatric evaluation is necessary to determine eligibility.

  • Is Spravato covered by insurance?

    Yes, many insurance plans in Utah cover Spravato for treatment-resistant depression when criteria are met.

  • Can I drive after Spravato treatment?

    No. Patients must arrange transportation after each treatment session due to temporary side effects.

  • Will Insurance Cover Spravato in Utah?

    Spravato is covered by many major insurance plans in Utah, including commercial insurance and Medicare in many cases.


    Our team assists patients with:


    • Insurance verification
    • Prior authorization for Spravato treatment
    • Out-of-pocket cost estimates
    • Coordination with insurance providers

    We work to make Spravato treatment in St. George as accessible and transparent as possible.

Schedule a Spravato Consultation in St. George, Utah


If you are searching for Spravato treatment Foundations Psychiatry can help you explore whether esketamine therapy is right for you.


Contact our office to schedule a consultation and learn more about treatment options for depression in Southern Utah.